Clinical Resources

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Blood Management

Information provided on this website is not intended to make claims that the products are safe and effective for any use other than those explicitly described in the Instructions for Use. Clinicians should refer to the Instructions for Use or Owner’s Manuals for complete information on the intended use of any product mentioned in this website.

FROM YOUR PEERS
JOURNAL ARTICLES

STUDY OVERVIEW: Study Demonstrates That Low Prime Volume Oxygenator Significantly Reduces Hemodilution
A study published in Perfusion confirms the beneficial effects of reducing circuit prime volume to reduce hemodilution during CPB.

BEST PRACTICE: Experts Share Tips To Achieve Blood Savings
Industry experts present clinical topics that are top-of-mind for perfusionists and the highlights are shared in this article.

STUDY: Children's Hospital Studies New Oxygenator with Integrated Arterial Filter
Joseph Deptula, CCP, Children's Hospital, found that the CAPIOX FX05 Oxygenator significantly reduced CPB prime volumes and surface area while reducing blood donor exposure; all without compromising patient safety.

CLINICAL STUDY: Prescriptive Patient Extracorporeal Circuit and Oxygenator Sizing Reduces Hemodilution and Allogeneic Blood Product Transfusion during Adult Cardiac Surgery. JECT. 2013; 45:167-172. Bronson S, et al. (PDF)

ABSTRACT: Beneficial Effects of Modern Perfusion Concepts in Aortic Valve and Aortic Root Surgery. Perfusion 2009;24: 37-44, Kutschka, et al.
In this 170-patient study, the use of the ROCSafe™ Hybrid Perfusion System was found to reduce side effects of standard extracorporeal circulation.

ABSTRACT: Blood Separation with Two Different Autotransfusion Devices: Effects on Blood Cell Quality and Coagulation Variables. Int. J Artif Organs, Dec 1998; 2: 820-4. Rosalski, et al.
The authors compare the Fresenius C.A.T.S System with another device and found that C.A.T.S had a higher platelet recovery rate and higher platelet concentration.

ABSTRACT: Investigation of Blood Compatibility of PMEA-Coated Extracorporeal Circuits. Journal of Bioactive and Compatible Polymers, Vol 17, Sept 2002. Kocakulak M, et al.
In a study comparing PMEA-coated and uncoated oxygenators, the authors found greater retention of clotting factors and platelets and less post-op hemorrhaging when using PMEA-coated oxygenators.

ABSTRACT: Emerging Technologies in Biocompatible Surface Modifying Additives: Quest for Physiologic CPB. Cardiovascular and Hematological Agents. 2004; Vol. 2:No 4. Gunaydin S, et al.
The authors compare surface coatings, including Xcoating, in 155 CPB cases for chemical composition, biomaterial evaluation and clinical efficacy.

ABSTRACT: Biocompatibility of Poly (2-methoxyethylacrylate) Coating for Cardiopulmonary Bypass. Annals Thoracic Cardiovascular Surgery, 2003, Volume 9, No 1. Noguchi, et al.
The authors compare the biocompatibility of PMEA-coated and heparin-coated circuits by measuring several inflammatory markers. Results indicate PMEA-coated circuits are as biocompatible as heparin coated circuits.

ABSTRACT: Xcoating: A New Biopassive Polymer Coating. Canadian Perfusion Canadienne, Volume 11, No 2, June 2001. Schiel, et al.
This paper explains the mechanism and benefits of Xcoating.

ABSTRACT: Non-Pharmacologic Therapeutic Strategies for Reducing Complications of Cardiopulmonary Bypass. Filtration 2005; 1(2):95-106. Gunaydin S, et al.
This study of 225 patients undergoing CPB concludes that the use of circuits with leukocyte filtration and Xcoating provides clinically significant benefits for high risk patients.

ABSTRACT: Intraoperative Autotransfusion in Small Children: An In-vitro Investigation to Study its Feasibility. Anesth Analg, April 1999; 88(4): 763-6. Booke, et al.
This in-vitro study demonstrates the ability of the Fresenius C.A.T.S System to produce high quality HCT independent of blood volume suggesting the feasibility of IAT in small children.

ABSTRACT: Quality of Processed Blood for Autotransfusion. JECT March 2000; 32: 11-9. Shulman, et al.
The authors evaluate the quality of processed blood using several parameters and demonstrate that the C.A.T.S System has a high washout efficiency and produces consistently high HCT at high flow rates.